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Piezo1 and G(q)/G(11) promote endothelial inflammation depending on flow pattern and integrin activation
The vascular endothelium is constantly exposed to mechanical forces, including fluid shear stress exerted by the flowing blood. Endothelial cells can sense different flow patterns and convert the mechanical signal of laminar flow into atheroprotective signals, including eNOS activation, whereas dist...
| Autores principales: | , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Rockefeller University Press
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6170174/ https://www.ncbi.nlm.nih.gov/pubmed/30194266 http://dx.doi.org/10.1084/jem.20180483 |