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System immunology-based identification of blood transcriptional modules correlating to antibody responses in sheep

Lacking immunogenicity, inactivated vaccines require potent adjuvants. To understand their effects, we used a system immunology-based analysis of ovine blood transcriptional modules (BTMs) to dissect innate immune responses relating to either antibody or haptoglobin levels. Using inactivated foot-an...

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Detalles Bibliográficos
Autores principales: Braun, Roman Othmar, Brunner, Livia, Wyler, Kurt, Auray, Gaël, García-Nicolás, Obdulio, Python, Sylvie, Zumkehr, Beatrice, Gaschen, Véronique, Stoffel, Michael Hubert, Collin, Nicolas, Barnier-Quer, Christophe, Bruggmann, Rémy, Summerfield, Artur
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6170373/
https://www.ncbi.nlm.nih.gov/pubmed/30302283
http://dx.doi.org/10.1038/s41541-018-0078-0