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Nuclear expansion and pore opening are instant signs of neuronal hypoxia and can identify poorly fixed brains
The initial phase of neuronal death is not well characterized. Here, we show that expansion of the nuclear membrane without losing its integrity along with peripheralization of chromatin are immediate signs of neuronal injury. Importantly, these changes can be identified with commonly used nuclear s...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6170374/ https://www.ncbi.nlm.nih.gov/pubmed/30282977 http://dx.doi.org/10.1038/s41598-018-32878-1 |