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Glycerophosphatidylcholine PC(36:1) absence and 3′-phosphoadenylate (pAp) accumulation are hallmarks of the human glioma metabolome

Glioma is the most prevalent malignant brain tumor. A comprehensive analysis of the glioma metabolome is still lacking. This study aims to explore new special metabolites in glioma tissues. A non-targeted human glioma metabolomics was performed by UPLC-Q-TOF/MS. The gene expressions of 18 enzymes as...

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Detalles Bibliográficos
Autores principales: Li, Wenchen, Jia, Hongmei, Li, Qi, Cui, Jiayue, Li, Ri, Zou, Zhongmei, Hong, Xinyu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6170378/
https://www.ncbi.nlm.nih.gov/pubmed/30283018
http://dx.doi.org/10.1038/s41598-018-32847-8