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Mutation, methylation, and gene expression profiles in dup(1q)-positive pediatric B-cell precursor acute lymphoblastic leukemia

High-throughput sequencing was applied to investigate the mutation/methylation patterns on 1q and gene expression profiles in pediatric B-cell precursor acute lymphoblastic leukemia (BCP ALL) with/without (w/wo) dup(1q). Sequencing of the breakpoint regions and all exons on 1q in seven dup(1q)-posit...

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Detalles Bibliográficos
Autores principales: Gunnarsson, Rebeqa, Dilorenzo, Sebastian, Lundin-Ström, Kristina B, Olsson, Linda, Biloglav, Andrea, Lilljebjörn, Henrik, Rissler, Marianne, Wahlberg, Per, Lundmark, Anders, Castor, Anders, Behrendtz, Mikael, Fioretos, Thoas, Paulsson, Kajsa, Isaksson, Anders, Johansson, Bertil
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6170391/
https://www.ncbi.nlm.nih.gov/pubmed/29626196
http://dx.doi.org/10.1038/s41375-018-0092-2