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Dysregulated iron metabolism in polycythemia vera: etiology and consequences

Polycythemia vera (PV) is a chronic myeloproliferative neoplasm. Virtually all PV patients are iron deficient at presentation and/or during the course of their disease. The co-existence of iron deficiency and polycythemia presents a physiological disconnect. Hepcidin, the master regulator of iron me...

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Detalles Bibliográficos
Autores principales: Ginzburg, Yelena Z., Feola, Maria, Zimran, Eran, Varkonyi, Judit, Ganz, Tomas, Hoffman, Ronald
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6170398/
https://www.ncbi.nlm.nih.gov/pubmed/30042411
http://dx.doi.org/10.1038/s41375-018-0207-9