Gut Colonization with Methanogenic Archaea Lowers Plasma Trimethylamine N-oxide Concentrations in Apolipoprotein e−/− Mice

A mechanistic link between trimethylamine N-oxide (TMAO) and atherogenesis has been reported. TMAO is generated enzymatically in the liver by the oxidation of trimethylamine (TMA), which is produced from dietary choline, carnitine and betaine by gut bacteria. It is known that certain members of meth...

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Detalles Bibliográficos
Autores principales: Ramezani, Ali, Nolin, Thomas D., Barrows, Ian R., Serrano, Myrna G., Buck, Gregory A., Regunathan-Shenk, Renu, West, Raymond E., Latham, Patricia S., Amdur, Richard, Raj, Dominic S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6170401/
https://www.ncbi.nlm.nih.gov/pubmed/30283097
http://dx.doi.org/10.1038/s41598-018-33018-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6170401/
https://www.ncbi.nlm.nih.gov/pubmed/30283097
http://dx.doi.org/10.1038/s41598-018-33018-5

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