STAT3 associates with vacuolar H(+)-ATPase and regulates cytosolic and lysosomal pH

Dysregulated intracellular pH is emerging as a hallmark of cancer. In spite of their acidic environment and increased acid production, cancer cells maintain alkaline intracellular pH that promotes cancer progression by inhibiting apoptosis and increasing glycolysis, cell growth, migration, and invas...

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Detalles Bibliográficos
Autores principales: Liu, Bin, Palmfeldt, Johan, Lin, Lin, Colaço, Alexandria, Clemmensen, Knut K. B., Huang, Jinrong, Xu, Fengping, Liu, Xin, Maeda, Kenji, Luo, Yonglun, Jäättelä, Marja
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6170402/
https://www.ncbi.nlm.nih.gov/pubmed/30127373
http://dx.doi.org/10.1038/s41422-018-0080-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6170402/
https://www.ncbi.nlm.nih.gov/pubmed/30127373
http://dx.doi.org/10.1038/s41422-018-0080-0

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