CCAAT/enhancer-binding protein-β functions as a negative regulator of Wnt/β-catenin signaling through activation of AXIN1 gene expression

Axin1, a concentration-limiting component of the β-catenin destruction complex, negatively regulates the Wnt/β-catenin pathway. Axin1 concentration is reported to be regulated by proteasomal degradation; however, its transcriptional regulation has not yet been reported. Here, we demonstrated that CC...

Descripción completa

Detalles Bibliográficos
Autores principales: Park, Seoyoung, Lee, Mi-Sun, Gwak, Jungsug, Choi, Tae-Ik, Lee, Youngseok, Ju, Bong Gun, Kim, Cheol-Hee, Oh, Sangtaek
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6170413/
https://www.ncbi.nlm.nih.gov/pubmed/30283086
http://dx.doi.org/10.1038/s41419-018-1072-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6170413/
https://www.ncbi.nlm.nih.gov/pubmed/30283086
http://dx.doi.org/10.1038/s41419-018-1072-1

Ejemplares similares