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CCAAT/enhancer-binding protein-β functions as a negative regulator of Wnt/β-catenin signaling through activation of AXIN1 gene expression

Axin1, a concentration-limiting component of the β-catenin destruction complex, negatively regulates the Wnt/β-catenin pathway. Axin1 concentration is reported to be regulated by proteasomal degradation; however, its transcriptional regulation has not yet been reported. Here, we demonstrated that CC...

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Detalles Bibliográficos
Autores principales:	Park, Seoyoung, Lee, Mi-Sun, Gwak, Jungsug, Choi, Tae-Ik, Lee, Youngseok, Ju, Bong Gun, Kim, Cheol-Hee, Oh, Sangtaek
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6170413/ https://www.ncbi.nlm.nih.gov/pubmed/30283086 http://dx.doi.org/10.1038/s41419-018-1072-1

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