Novel engineered, membrane-localized variants of vascular endothelial growth factor (VEGF) protect retinal ganglion cells: a proof-of-concept study

Endogenous vascular endothelial growth factor (VEGF-A) can protect retinal ganglion cells (RGC) from stress-induced cell death in ocular hypertensive glaucoma. To exploit the neuroprotective function of VEGF-A for therapeutic application in ocular disorders such as glaucoma while minimizing unwanted...

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Detalles Bibliográficos
Autores principales: Shen, Junhui, Xiao, Ru, Bair, Jeffrey, Wang, Fang, Vandenberghe, Luk H., Dartt, Darlene, Baranov, Petr, Ng, Yin Shan Eric
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6170416/
https://www.ncbi.nlm.nih.gov/pubmed/30282966
http://dx.doi.org/10.1038/s41419-018-1049-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6170416/
https://www.ncbi.nlm.nih.gov/pubmed/30282966
http://dx.doi.org/10.1038/s41419-018-1049-0

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