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Suppression of SUN2 by DNA methylation is associated with HSCs activation and hepatic fibrosis

Hepatic myofibroblasts, activated hepatic stellate cells (HSCs), are the main cell type of extracellular matrix (ECM) deposition during hepatic fibrosis. Aberrant DNA methylation-regulated HSCs activation in liver fibrogenesis has been reported, but the functional roles and mechanisms of DNA methyla...

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Detalles Bibliográficos
Autores principales: Chen, Xin, Li, Wan-Xia, Chen, Yu, Li, Xiao-Feng, Li, Hai-Di, Huang, Hui-Min, Bu, Fang-Tian, Pan, Xue-Yin, Yang, Yang, Huang, Cheng, Meng, Xiao-Ming, Li, Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6170444/
https://www.ncbi.nlm.nih.gov/pubmed/30282980
http://dx.doi.org/10.1038/s41419-018-1032-9