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Inhibition of the gyrA promoter by transcription-coupled DNA supercoiling in Escherichia coli
The E. coli gyrA promoter (P(gyrA)) is a DNA supercoiling sensitive promoter, stimulated by relaxation of DNA templates, and inhibited by (−) DNA supercoiling in bacteria. However, whether P(gyrA) can be inhibited by transient and localized transcription-coupled DNA supercoiling (TCDS) has not been...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6170449/ https://www.ncbi.nlm.nih.gov/pubmed/30282997 http://dx.doi.org/10.1038/s41598-018-33089-4 |