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Long noncoding RNA MEG3 regulates LATS2 by promoting the ubiquitination of EZH2 and inhibits proliferation and invasion in gallbladder cancer

Gallbladder cancer (GBC) is the most common type of biliary tract cancer worldwide. Long noncoding RNAs (lncRNAs) play essential roles in physiological and pathological development. LncRNA MEG3, a tumor suppressor, has been reported to play important roles in some cancers, but the role of MEG3 in GB...

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Detalles Bibliográficos
Autores principales: Jin, Longyang, Cai, Qiang, Wang, Shouhua, Wang, Shuqing, Mondal, Tanmoy, Wang, Jiandong, Quan, Zhiwei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6170488/
https://www.ncbi.nlm.nih.gov/pubmed/30282996
http://dx.doi.org/10.1038/s41419-018-1064-1