Protein-protein interactions reveal key canonical pathways, upstream regulators, interactome domains, and novel targets in ALS

Developing effective treatment strategies for neurodegenerative diseases require an understanding of the underlying cellular pathways that lead to neuronal vulnerability and progressive degeneration. To date, numerous mutations in 147 distinct genes are identified to be “associated” with, “modifier”...

Descripción completa

Detalles Bibliográficos
Autores principales: Dervishi, Ina, Gozutok, Oge, Murnan, Kevin, Gautam, Mukesh, Heller, Daniel, Bigio, Eileen, Ozdinler, P. Hande
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6170493/
https://www.ncbi.nlm.nih.gov/pubmed/30283000
http://dx.doi.org/10.1038/s41598-018-32902-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6170493/
https://www.ncbi.nlm.nih.gov/pubmed/30283000
http://dx.doi.org/10.1038/s41598-018-32902-4

Ejemplares similares