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Protein-protein interactions reveal key canonical pathways, upstream regulators, interactome domains, and novel targets in ALS
Developing effective treatment strategies for neurodegenerative diseases require an understanding of the underlying cellular pathways that lead to neuronal vulnerability and progressive degeneration. To date, numerous mutations in 147 distinct genes are identified to be “associated” with, “modifier”...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6170493/ https://www.ncbi.nlm.nih.gov/pubmed/30283000 http://dx.doi.org/10.1038/s41598-018-32902-4 |