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Reprogramming of regulatory network using expression uncovers sex-specific gene regulation in Drosophila

Gene regulatory networks (GRNs) describe regulatory relationships between transcription factors (TFs) and their target genes. Computational methods to infer GRNs typically combine evidence across different conditions to infer context-agnostic networks. We develop a method, Network Reprogramming usin...

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Detalles Bibliográficos
Autores principales: Wang, Yijie, Cho, Dong-Yeon, Lee, Hangnoh, Fear, Justin, Oliver, Brian, Przytycka, Teresa M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6170494/
https://www.ncbi.nlm.nih.gov/pubmed/30283019
http://dx.doi.org/10.1038/s41467-018-06382-z