A microfluidic chip-based co-culture of fibroblast-like synoviocytes with osteoblasts and osteoclasts to test bone erosion and drug evaluation

Targeting fibroblast-like synoviocyte (FLS) migration and invasion-mediated bone erosion is a promising clinical strategy for the treatment of rheumatoid arthritis (RA). Drug sensitivity testing is fundamental to this scheme. We designed a microfluidic chip-based, cell co-cultured platform to mimic...

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Detalles Bibliográficos
Autores principales: Ma, Hui-Peng, Deng, Xue, Chen, Deng-Yi, Zhu, Di, Tong, Jin-Ling, Zhao, Ting, Ma, Jin-Hui, Liu, Yan-Qiu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society 2018
Materias:
Cellular and Molecular Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6170564/
https://www.ncbi.nlm.nih.gov/pubmed/30839692
http://dx.doi.org/10.1098/rsos.180528

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6170564/
https://www.ncbi.nlm.nih.gov/pubmed/30839692
http://dx.doi.org/10.1098/rsos.180528

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