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New Insights Into the Role of Ca(v)2 Protein Family in Calcium Flux Deregulation in Fmr1-KO Neurons

Fragile X syndrome (FXS), the most common form of inherited intellectual disability (ID) and a leading cause of autism, results from the loss of expression of the Fmr1 gene which encodes the RNA-binding protein Fragile X Mental Retardation Protein (FMRP). Among the thousands mRNA targets of FMRP, nu...

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Detalles Bibliográficos
Autores principales: Castagnola, Sara, Delhaye, Sébastien, Folci, Alessandra, Paquet, Agnès, Brau, Frédéric, Duprat, Fabrice, Jarjat, Marielle, Grossi, Mauro, Béal, Méline, Martin, Stéphane, Mantegazza, Massimo, Bardoni, Barbara, Maurin, Thomas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6170614/
https://www.ncbi.nlm.nih.gov/pubmed/30319351
http://dx.doi.org/10.3389/fnmol.2018.00342