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Polyphyllin I Ameliorates Collagen-Induced Arthritis by Suppressing the Inflammation Response in Macrophages Through the NF-κB Pathway

Background: Rheumatoid arthritis (RA) is a chronic autoimmune disorder, characterized by an increased number of M1-like macrophages in the joints. Polyphyllin I (PPI), one of the main components in the Rhizoma of Paris polyphyllin, displays a selective inhibitory effect on various tumor cells. Here...

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Detalles Bibliográficos
Autores principales: Wang, Qiong, Zhou, Xin, Zhao, Yongjian, Xiao, Jun, Lu, Yao, Shi, Qi, Wang, Yongjun, Wang, Hongyan, Liang, Qianqian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6170622/
https://www.ncbi.nlm.nih.gov/pubmed/30319603
http://dx.doi.org/10.3389/fimmu.2018.02091