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Gene expression and single nucleotide polymorphism of ATP7B are associated with platinum-based chemotherapy response in non-small cell lung cancer patients

Objectives: Platinum-based chemotherapy is first-line treatment for non-small cell lung cancer (NSCLC) patients. The efficacy is limited by drug resistance. Recent studies suggest that ATP7B, a copper efflux transporter, may be involved in platinum resistance. However, the clinical significance of A...

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Detalles Bibliográficos
Autores principales: Li, Yue-Qin, Chen, Juan, Yin, Ji-Ye, Liu, Zhao-Qian, Li, Xiang-Ping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6171024/
https://www.ncbi.nlm.nih.gov/pubmed/30310510
http://dx.doi.org/10.7150/jca.26286