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Stem cell factor induces polarization of microglia to the neuroprotective phenotype in vitro

Microglia are classified mainly into the M1 or M2 phenotypes, which evoke either proinflammatory or neuroprotective responses. Given the association of microglia with the pathogenesis of neuronal diseases, they are in focus as therapeutic targets for the treatment of such conditions. Stem cell facto...

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Detalles Bibliográficos
Autores principales: Terashima, Tomoya, Nakae, Yuki, Katagi, Miwako, Okano, Junko, Suzuki, Yoshihisa, Kojima, Hideto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6171080/
https://www.ncbi.nlm.nih.gov/pubmed/30294687
http://dx.doi.org/10.1016/j.heliyon.2018.e00837