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Identity and validity of conserved B cell epitopes of filovirus glycoprotein: towards rapid diagnostic testing for Ebola and possibly Marburg virus disease

BACKGROUND: Ebolavirus and Marburgvirus are genera of the virus family Filoviridae. Filoviruses cause rare but fatal viral hemorrhagic fevers (VHFs) in remote villages of equatorial Africa with potential for regional and international spread. Point-of-care (POC) rapid diagnostic tests (RDTs) are cri...

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Detalles Bibliográficos
Autores principales: Babirye, Peace, Musubika, Carol, Kirimunda, Samuel, Downing, Robert, Lutwama, Julian J, Mbidde, Edward K, Weyer, Jacqueline, Paweska, Janusz T, Joloba, Moses L, Wayengera, Misaki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6171133/
https://www.ncbi.nlm.nih.gov/pubmed/30285648
http://dx.doi.org/10.1186/s12879-018-3409-x