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Cellular network modeling and single cell gene expression analysis reveals novel hepatic stellate cell phenotypes controlling liver regeneration dynamics

BACKGROUND: Recent results from single cell gene and protein regulation studies are starting to uncover the previously underappreciated fact that individual cells within a population exhibit high variability in the expression of mRNA and proteins (i.e., molecular variability). By combining cellular...

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Detalles Bibliográficos
Autores principales: Cook, Daniel, Achanta, Sirisha, Hoek, Jan B., Ogunnaike, Babatunde A., Vadigepalli, Rajanikanth
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6171157/
https://www.ncbi.nlm.nih.gov/pubmed/30285726
http://dx.doi.org/10.1186/s12918-018-0605-7