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Protecting Pax6 3′ UTR from MicroRNA-7 Partially Restores PAX6 in Islets from an Aniridia Mouse Model

Aniridia is a rare congenital syndrome that is associated with reduced visual acuity and progressive loss of vision. Aniridia patients may also develop systemic health issues associated with defects in the pancreas, digestive, and central nervous systems. The spectrum of symptoms associated with ani...

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Detalles Bibliográficos
Autores principales: Yongblah, Kevin, Alford, Spencer C., Ryan, Bridget C., Chow, Robert L., Howard, Perry L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6171161/
https://www.ncbi.nlm.nih.gov/pubmed/30290306
http://dx.doi.org/10.1016/j.omtn.2018.08.018