Combining controls can improve power in two-stage association studies

BACKGROUND: High dimensional case control studies are ubiquitous in the biological sciences, particularly genomics. To maximise power while constraining cost and to minimise type-1 error rates, researchers typically seek to replicate findings in a second experiment on independent cohorts before proc...

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Detalles Bibliográficos
Autor principal: Liley, James
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Methodology Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6171163/
https://www.ncbi.nlm.nih.gov/pubmed/30285617
http://dx.doi.org/10.1186/s12863-018-0675-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6171163/
https://www.ncbi.nlm.nih.gov/pubmed/30285617
http://dx.doi.org/10.1186/s12863-018-0675-y

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