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Combining controls can improve power in two-stage association studies
BACKGROUND: High dimensional case control studies are ubiquitous in the biological sciences, particularly genomics. To maximise power while constraining cost and to minimise type-1 error rates, researchers typically seek to replicate findings in a second experiment on independent cohorts before proc...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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BioMed Central
2018
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6171163/ https://www.ncbi.nlm.nih.gov/pubmed/30285617 http://dx.doi.org/10.1186/s12863-018-0675-y |