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Translocated duplication of a targeted chromosomal segment enhances gene expression at the duplicated site and results in phenotypic changes in Aspergillus oryzae

BACKGROUND: Translocated chromosomal duplications occur spontaneously in many organisms; segmental duplications of large chromosomal regions are expected to result in phenotypic changes because of gene dosage effects. Therefore, experimentally generated segmental duplications in targeted chromosomal...

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Detalles Bibliográficos
Autores principales: Takahashi, Tadashi, Ogawa, Masahiro, Sato, Atsushi, Koyama, Yasuji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6171174/
https://www.ncbi.nlm.nih.gov/pubmed/30305913
http://dx.doi.org/10.1186/s40694-018-0061-6