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Nucleus basalis of Meynert degeneration precedes and predicts cognitive impairment in Parkinson’s disease

Currently, no reliable predictors of cognitive impairment in Parkinson’s disease exist. We hypothesized that microstructural changes at grey matter T(1)-weighted MRI and diffusion tensor imaging in the cholinergic system nuclei and associated limbic pathways underlie cognitive impairment in Parkinso...

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Detalles Bibliográficos
Autores principales: Schulz, Jonathan, Pagano, Gennaro, Fernández Bonfante, Juan Alberto, Wilson, Heather, Politis, Marios
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6171218/
https://www.ncbi.nlm.nih.gov/pubmed/29701787
http://dx.doi.org/10.1093/brain/awy072