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Notch2 signal is required for the maintenance of canine hemangiosarcoma cancer stem cell-like cells

BACKGROUND: Hemangiosarcoma (HSA) is a malignant tumor derived from endothelial cells which usually shows poor prognosis due to its high invasiveness, metastatic rate and severe hemorrhage from tumor ruptures. Since the pathogenesis of HSA is not yet complete, further understanding of its molecular...

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Detalles Bibliográficos
Autores principales: Aoshima, Keisuke, Fukui, Yuki, Gulay, Kevin Christian Montecillo, Erdemsurakh, Ochbayar, Morita, Atsuya, Kobayashi, Atsushi, Kimura, Takashi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6171240/
https://www.ncbi.nlm.nih.gov/pubmed/30285832
http://dx.doi.org/10.1186/s12917-018-1624-8