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PD-L1/PD-1 crosstalk in colorectal cancer: are we targeting the right cells?

BACKGROUND: The analysis of tumour-infiltrating immune cells within patients’ tumour samples in colorectal cancer (CRC) has become an independent predictor of patient survival. The tumour microenvironment and the immune checkpoints, such as PD-L1/PD-1, are relevant to the prognoses and also appear t...

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Detalles Bibliográficos
Autores principales: Cantero-Cid, Ramón, Casas-Martin, José, Hernández-Jiménez, Enrique, Cubillos-Zapata, Carolina, Varela-Serrano, Aníbal, Avendaño-Ortiz, José, Casarrubios, Marta, Montalbán-Hernández, Karla, Villacañas-Gil, Ignacio, Guerra-Pastrián, Laura, Peinado, Begoña, Marcano, Cristóbal, Aguirre, Luis A, López-Collazo, Eduardo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6171318/
https://www.ncbi.nlm.nih.gov/pubmed/30285662
http://dx.doi.org/10.1186/s12885-018-4853-0