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Genetic Variations and Cisplatin Nephrotoxicity: A Systematic Review

Background: Nephrotoxicity is a notable adverse effect in cisplatin treated patients characterized by tubular injury and/or increased serum creatinine (SCr) with incidence varying from 20 to 70%. Pharmacogenomics has been shown to identify strongly predictive genetic markers to help determine which...

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Detalles Bibliográficos
Autores principales: Zazuli, Zulfan, Vijverberg, Susanne, Slob, Elise, Liu, Geoffrey, Carleton, Bruce, Veltman, Joris, Baas, Paul, Masereeuw, Rosalinde, Maitland-van der Zee, Anke-Hilse
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6171472/
https://www.ncbi.nlm.nih.gov/pubmed/30319427
http://dx.doi.org/10.3389/fphar.2018.01111