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Immune Checkpoint Inhibitors for the Treatment of Central Nervous System (CNS) Metastatic Disease
While the CNS has long been viewed as an immune-privileged environment, a paradigm shift in neuro-immunology has elevated the role of systemic immunotherapy for the treatment of metastatic disease. Increasing knowledge regarding the presence of a CNS lymphatic system and the physical and biochemical...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2018
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6171475/ https://www.ncbi.nlm.nih.gov/pubmed/30319977 http://dx.doi.org/10.3389/fonc.2018.00414 |