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Modifying Intestinal Integrity and Micro Biome in Severe Malnutrition with Legume-Based Feeds (MIMBLE 2.0): protocol for a phase II refined feed and intervention trial

Background: Changes in intestinal mucosal integrity and gut microbial balance occur in severe acute malnutrition (SAM), resulting in treatment failure and adverse clinical outcomes (gram-negative sepsis, diarrhoea and high case-fatality). Transient lactose intolerance, due to loss of intestinal brus...

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Detalles Bibliográficos
Autores principales: Walsh, Kevin, Calder, Nuala, Olupot-Olupot, Peter, Ssenyondo, Tonny, Okiror, William, Okalebo, Charles Bernard, Muhindo, Rita, Mpoya, Ayub, Holmes, Elaine, Marchesi, Julian, Delamare de la Villenaise de Chenevarin, Gael, Frost, Gary, Maitland, Kathryn
Formato: Online Artículo Texto
Lenguaje:English
Publicado: F1000 Research Limited 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6171552/
https://www.ncbi.nlm.nih.gov/pubmed/30345381
http://dx.doi.org/10.12688/wellcomeopenres.14706.1