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Effect of tranexamic acid on coagulation and fibrinolysis in women with postpartum haemorrhage (WOMAN-ETAC): a single-centre, randomised, double-blind, placebo-controlled trial

Background: Postpartum haemorrhage (PPH) is a leading cause of maternal death. The WOMAN trial showed that tranexamic acid (TXA) reduces death due to bleeding in women with PPH. We evaluated the effect of TXA on fibrinolysis and coagulation in a sample of WOMAN trial participants. Methods: Adult wom...

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Detalles Bibliográficos
Autores principales: Shakur-Still, Haleema, Roberts, Ian, Fawole, Bukola, Kuti, Modupe, Olayemi, Oladapo O., Bello, Adenike, Huque, Sumaya, Ogunbode, Olayinka, Kotila, Taiwo, Aimakhu, Chris, Okunade, Olujide A., Olutogun, Tolulase, Adetayo, Cecilia O., Dallaku, Kastriot, Mansmann, Ulrich, Hunt, Beverley J., Pepple, Tracey, Balogun, Eni
Formato: Online Artículo Texto
Lenguaje:English
Publicado: F1000 Research Limited 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6171555/
https://www.ncbi.nlm.nih.gov/pubmed/30345385
http://dx.doi.org/10.12688/wellcomeopenres.14722.1