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FUT2 secretor genotype and susceptibility to infections and chronic conditions in the ALSPAC cohort

Background: The FUT2 (fucosyltransferase-2) gene determines blood group secretor status. Being homozygous for the inactive “non-secretor” rs601338(A) allele confers resistance to certain infections (e.g. Norovirus, Rotavirus) and susceptibility to others (e.g. Haemophilus influenza, Streptococcus pn...

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Detalles Bibliográficos
Autores principales: Azad, Meghan B., Wade, Kaitlin H., Timpson, Nicholas J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: F1000 Research Limited 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6171556/
https://www.ncbi.nlm.nih.gov/pubmed/30345375
http://dx.doi.org/10.12688/wellcomeopenres.14636.2