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Inhibition of Ubiquitin-Specific Proteases as a Novel Anticancer Therapeutic Strategy
Dysfunction or dysregulation of the ubiquitin proteasome system (UPS) is closely related to tumorigenesis and the development of multiple cancers. Targeting the UPS provides a new anticancer therapeutic strategy, but clinically available UPS-targeted inhibitors, including lenalidomide and bortezomib...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6171565/ https://www.ncbi.nlm.nih.gov/pubmed/30319415 http://dx.doi.org/10.3389/fphar.2018.01080 |