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Inhibition of Ubiquitin-Specific Proteases as a Novel Anticancer Therapeutic Strategy

Dysfunction or dysregulation of the ubiquitin proteasome system (UPS) is closely related to tumorigenesis and the development of multiple cancers. Targeting the UPS provides a new anticancer therapeutic strategy, but clinically available UPS-targeted inhibitors, including lenalidomide and bortezomib...

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Detalles Bibliográficos
Autores principales:	Yuan, Tao, Yan, Fangjie, Ying, Meidan, Cao, Ji, He, Qiaojun, Zhu, Hong, Yang, Bo
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2018
Materias:	Pharmacology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6171565/ https://www.ncbi.nlm.nih.gov/pubmed/30319415 http://dx.doi.org/10.3389/fphar.2018.01080

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