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Cocaine Exposure Modulates Perineuronal Nets and Synaptic Excitability of Fast-Spiking Interneurons in the Medial Prefrontal Cortex

We previously reported that perineuronal nets (PNNs) are required for cocaine-associated memories. Perineuronal nets are extracellular matrix that primarily surrounds parvalbumin (PV)-containing, GABAergic fast-spiking interneurons (FSIs) in the medial prefrontal cortex (mPFC). Here we measured the...

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Detalles Bibliográficos
Autores principales: Slaker, Megan L., Jorgensen, Emily T., Hegarty, Deborah M., Liu, Xinyue, Kong, Yan, Zhang, Fuming, Linhardt, Robert J., Brown, Travis E., Aicher, Sue A., Sorg, Barbara A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Society for Neuroscience 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6171740/
https://www.ncbi.nlm.nih.gov/pubmed/30294670
http://dx.doi.org/10.1523/ENEURO.0221-18.2018