Cyclin-dependent kinase 4 is a preclinical target for diet-induced obesity

When obesity is caused by consumption of a high-fat diet, the tumor suppressor pRb is phosphoinactivated in the neurons of the mediobasal hypothalamus, a brain area critical for energy-balance regulation. However, the functional relevance of pRb phosphoinactivation in the mediobasal hypothalamus to...

Descripción completa

Detalles Bibliográficos
Autores principales: Iqbal, Niloy Jafar, Lu, Zhonglei, Liu, Shun Mei, Schwartz, Gary J., Chua, Streamson, Zhu, Liang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6171799/
https://www.ncbi.nlm.nih.gov/pubmed/30185666
http://dx.doi.org/10.1172/jci.insight.123000

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6171799/
https://www.ncbi.nlm.nih.gov/pubmed/30185666
http://dx.doi.org/10.1172/jci.insight.123000

Ejemplares similares