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High-fat diet suppresses the positive effect of creatine supplementation on skeletal muscle function by reducing protein expression of IGF-PI3K-AKT-mTOR pathway

High-fat (HF) diets in combination with sedentary lifestyle represent one of the major public health concerns predisposing to obesity and diabetes leading to skeletal muscle atrophy, decreased fiber diameter and muscle mass with accumulation of fat tissue resulting in loss of muscle strength. One st...

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Detalles Bibliográficos
Autores principales: Ferretti, Renato, Moura, Eliezer Guimarães, dos Santos, Veridiana Carvalho, Caldeira, Eduardo José, Conte, Marcelo, Matsumura, Cintia Yuri, Pertille, Adriana, Mosqueira, Matias
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6171830/
https://www.ncbi.nlm.nih.gov/pubmed/30286093
http://dx.doi.org/10.1371/journal.pone.0199728