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Development of standard clinical endpoints for use in dengue interventional trials

Dengue is a major public health problem worldwide. Although several drug candidates have been evaluated in randomized controlled trials, none has been effective and at present, early recognition of severe dengue and timely supportive care are used to reduce mortality. While the first dengue vaccine...

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Detalles Bibliográficos
Autores principales: Tomashek, Kay M., Wills, Bridget, See Lum, Lucy Chai, Thomas, Laurent, Durbin, Anna, Leo, Yee-Sin, de Bosch, Norma, Rojas, Elsa, Hendrickx, Kim, Erpicum, Martin, Agulto, Liane, Jaenisch, Thomas, Tissera, Hasitha, Suntarattiwong, Piyarat, Collers, Beth Ann, Wallace, Derek, Schmidt, Alexander C., Precioso, Alexander, Narvaez, Federico, Thomas, Stephen J., Edelman, Robert, Siqueira, João Bosco, Cassetti, M. Cristina, Dempsey, Walla, Gubler, Duane J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6171842/
https://www.ncbi.nlm.nih.gov/pubmed/30286085
http://dx.doi.org/10.1371/journal.pntd.0006497