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miR-125b regulates chemotaxis and survival of bone marrow derived granulocytes in vitro and in vivo

The evolutionary conserved miR-125b is highly expressed in hematopoietic stem cells (HSC) enhancing self-renewal and survival. Accordingly, over-expression of miR-125b in HSC may induce myeloproliferative neoplasms and leukemia with long latency. During hematopoietic cell maturation miR-125b express...

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Detalles Bibliográficos
Autores principales: Lee, Chun-Wei, Schoenherr, Caroline, Battmer, Karin, Ganser, Arnold, Hilfiker-Kleiner, Denise, David, Sascha, Eder, Matthias, Scherr, Michaela
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6171867/
https://www.ncbi.nlm.nih.gov/pubmed/30286140
http://dx.doi.org/10.1371/journal.pone.0204942