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miR-125b regulates chemotaxis and survival of bone marrow derived granulocytes in vitro and in vivo
The evolutionary conserved miR-125b is highly expressed in hematopoietic stem cells (HSC) enhancing self-renewal and survival. Accordingly, over-expression of miR-125b in HSC may induce myeloproliferative neoplasms and leukemia with long latency. During hematopoietic cell maturation miR-125b express...
Autores principales: | Lee, Chun-Wei, Schoenherr, Caroline, Battmer, Karin, Ganser, Arnold, Hilfiker-Kleiner, Denise, David, Sascha, Eder, Matthias, Scherr, Michaela |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6171867/ https://www.ncbi.nlm.nih.gov/pubmed/30286140 http://dx.doi.org/10.1371/journal.pone.0204942 |
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