Cytoplasmic, nuclear, and total PBK/TOPK expression is associated with prognosis in colorectal cancer patients: A retrospective analysis based on immunohistochemistry stain of tissue microarrays

OBJECTIVE: PDZ-binding kinase/T-LAK cell-originated protein kinase (PBK/TOPK) regulates components of the cell cycle, including cell growth, immune responses, DNA damage repair, apoptosis, and inflammation. PBK/TOPK may also accelerate tumorigenesis in colorectal cancer. METHODS: We investigated the...

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Detalles Bibliográficos
Autores principales: Su, Tzu-Cheng, Chen, Chun-Yu, Tsai, Wen-Che, Hsu, Hui-Ting, Yen, Hsu-Heng, Sung, Wen-Wei, Chen, Chih-Jung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6171876/
https://www.ncbi.nlm.nih.gov/pubmed/30286126
http://dx.doi.org/10.1371/journal.pone.0204866

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6171876/
https://www.ncbi.nlm.nih.gov/pubmed/30286126
http://dx.doi.org/10.1371/journal.pone.0204866

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