Epigallocatechin-3 gallate prevents pressure overload-induced heart failure by up-regulating SERCA2a via histone acetylation modification in mice

Heart failure is a common, costly, and potentially fatal condition. The cardiac sarcoplasmic reticulum Ca-ATPase (SERCA2a) plays a critical role in the regulation of cardiac function. Previously, low SERCA2a expression was revealed in mice with heart failure. Epigallocatechin-3-gallate (EGCG) can fu...

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Detalles Bibliográficos
Autores principales: Liu, Lifei, Zhao, Weian, Liu, Jianxia, Gan, Yi, Liu, Lingjuan, Tian, Jie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6171916/
https://www.ncbi.nlm.nih.gov/pubmed/30286210
http://dx.doi.org/10.1371/journal.pone.0205123

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6171916/
https://www.ncbi.nlm.nih.gov/pubmed/30286210
http://dx.doi.org/10.1371/journal.pone.0205123

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