NLRP6 negatively regulates pulmonary host defense in Gram-positive bacterial infection through modulating neutrophil recruitment and function

Gram-positive bacteria, including Staphylococcus aureus are endemic in the U.S., which cause life-threatening necrotizing pneumonia. Neutrophils are known to be critical for clearance of S. aureus infection from the lungs and extrapulmonary organs. Therefore, we investigated whether the NLRP6 inflam...

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Detalles Bibliográficos
Autores principales: Ghimire, Laxman, Paudel, Sagar, Jin, Liliang, Baral, Pankaj, Cai, Shanshan, Jeyaseelan, Samithamby
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6171945/
https://www.ncbi.nlm.nih.gov/pubmed/30248149
http://dx.doi.org/10.1371/journal.ppat.1007308

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6171945/
https://www.ncbi.nlm.nih.gov/pubmed/30248149
http://dx.doi.org/10.1371/journal.ppat.1007308

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