Cargando…

Hrg1 promotes heme-iron recycling during hemolysis in the zebrafish kidney

Heme-iron recycling from senescent red blood cells (erythrophagocytosis) accounts for the majority of total body iron in humans. Studies in cultured cells have ascribed a role for HRG1/SLC48A1 in heme-iron transport but the in vivo function of this heme transporter is unclear. Here we present geneti...

Descripción completa

Detalles Bibliográficos
Autores principales: Zhang, Jianbing, Chambers, Ian, Yun, Sijung, Phillips, John, Krause, Michael, Hamza, Iqbal
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6171960/
https://www.ncbi.nlm.nih.gov/pubmed/30248094
http://dx.doi.org/10.1371/journal.pgen.1007665