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Hrg1 promotes heme-iron recycling during hemolysis in the zebrafish kidney
Heme-iron recycling from senescent red blood cells (erythrophagocytosis) accounts for the majority of total body iron in humans. Studies in cultured cells have ascribed a role for HRG1/SLC48A1 in heme-iron transport but the in vivo function of this heme transporter is unclear. Here we present geneti...
Autores principales: | Zhang, Jianbing, Chambers, Ian, Yun, Sijung, Phillips, John, Krause, Michael, Hamza, Iqbal |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6171960/ https://www.ncbi.nlm.nih.gov/pubmed/30248094 http://dx.doi.org/10.1371/journal.pgen.1007665 |
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