Genome-wide association studies and CRISPR/Cas9-mediated gene editing identify regulatory variants influencing eyebrow thickness in humans

Hair plays an important role in primates and is clearly subject to adaptive selection. While humans have lost most facial hair, eyebrows are a notable exception. Eyebrow thickness is heritable and widely believed to be subject to sexual selection. Nevertheless, few genomic studies have explored its...

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Detalles Bibliográficos
Autores principales: Wu, Sijie, Zhang, Manfei, Yang, Xinzhou, Peng, Fuduan, Zhang, Juan, Tan, Jingze, Yang, Yajun, Wang, Lina, Hu, Yanan, Peng, Qianqian, Li, Jinxi, Liu, Yu, Guan, Yaqun, Chen, Chen, Hamer, Merel A., Nijsten, Tamar, Zeng, Changqing, Adhikari, Kaustubh, Gallo, Carla, Poletti, Giovanni, Schuler-Faccini, Lavinia, Bortolini, Maria-Cátira, Canizales-Quinteros, Samuel, Rothhammer, Francisco, Bedoya, Gabriel, González-José, Rolando, Li, Hui, Krutmann, Jean, Liu, Fan, Kayser, Manfred, Ruiz-Linares, Andres, Tang, Kun, Xu, Shuhua, Zhang, Liang, Jin, Li, Wang, Sijia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6171961/
https://www.ncbi.nlm.nih.gov/pubmed/30248107
http://dx.doi.org/10.1371/journal.pgen.1007640

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6171961/
https://www.ncbi.nlm.nih.gov/pubmed/30248107
http://dx.doi.org/10.1371/journal.pgen.1007640

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